Antabuse (disulfiram) is a prescription medicine that you may be able to use if you have trouble getting rid of your alcohol addiction. This medicine must not be given to anyone who is already in the state of intoxication, or people unaware of what this medicine is used for and therefore likely to have a drink after taking Antabuse. If you had a drink you are not supposed to take Antabuse within the next 12 hours, although an unpleasant reaction may occur even during up to 2 weeks after the treatment was stopped. If you have skin rash, metallic taste in the mouth, tiredness, acne, drowsiness, mild headache, and develop impotence, wait to see if these side effects go away. The side effects mentioned above are usually short-lived and do not need to be reported.